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ABFM NEWS - Radioterapia
 
Can protons improve SBRT for lung lesions? Dosimetric considerations.
 
The aim of the present study was to investigate potential dosimetric benefits of proton therapy for hypofractionated stereotactic body radiotherapy (SBRT)... [+ leia mais]
Colaborador: Camila Pessoa de Sales.
Fonte: Radiotherapy and Oncology.
 
 
Lung 4D-IMRT treatment planning: An evaluation of three methods applied to four-dimensional data sets.
 
"To compare 4D-dose distributions for IMRT planning on three data sets: a single 4D-CT phase, a 4D-CT phase with a density override to the tumor motion envelope (TME) volume, and the average intensity projection (AIP)... " [+ leia mais]
Colaborador: Camila Pessoa de Sales.
Fonte: Radiotherapy and Oncology.
 
 
Some implications of linear-quadratic-linear radiation dose-response with regard to hypofractionation.
 
Recent technological advances enable radiation therapy to be delivered in a highly conformal manner to targets located almost anywhere in the body. This capability has renewed the clinical interest in hypofractionation wherein the tumor is delivered a few fractions of very large dose per fraction... [+ leia mais]
Fonte: Medical Physics.
 
 
Accelerator beam data commissioning equipment and procedures: Report of the TG-106 of the Therapy Physics Committee of the AAPM.
 
For commissioning a linear accelerator for clinical use, medical physicists are faced with many challenges including the need for precision, a variety of testing methods, data validation, the lack of standards, and time constraints... [+ leia mais]
Fonte: Medical Physics.
 
 
EORTC 22972–26991/MRC BR10 trial: Fractionated stereotactic boost following conventional radiotherapy of high grade gliomas: Clinical and quality...
 
The EORTC trial No. 22972 investigated the role of an additional fractionated stereotactic boost (fSRT) to conventional radiotherapy for patients with high grade gliomas. A quality-assurance (QA) programme was run in conjunction with the study... [+ leia mais]
Colaborador: Camila Pessoa de Sales.
Fonte: Radiotherapy and Oncology.
 
 
A phase III study of accelerated versus conventional hypofractionated whole brain irradiation in patients of good performance status with brain met...
 
An accelerated prescription for whole brain irradiation (WBI) in the treatment of brain metastases has been reported to provide favourable survival in good performance status patients... [+ leia mais]
Colaborador: Camila Pessoa de Sales.
Fonte: Radiotherapy and Oncology.
 
 
Proposed Rectal Dose Constraints for Patients Undergoing Definitive Whole Pelvic Radiotherapy for Clinically Localized Prostate Cancer.
 
Although several institutions have reported rectal dose constraints according to threshold toxicity, the plethora of trials has resulted in multiple, confusing dose–volume histogram recommendations. A set of standardized, literature-based constraints for patients undergoing whole pelvic radiotherapy (RT) for prostate cancer would help guide the practice of prostate RT... [+ leia mais]
Fonte: Int J Radiat Oncol Biol Phys.
 
 
Magnetic Resonance Imaging Appearances in the Postoperative Breast: The Clinical Target Volume–Tumor and Its Relationship to the Chest Wall.
 
To describe and measure the postoperative complexes and their relationship to the chest wall in 100 randomly chosen MRI breast scans, to attempt a better understanding of the changes taking place in the postoperative breast... [+ leia mais]
Fonte: Int J Radiat Oncol Biol Phys.
 
 
Online MRI guidance for healthy tissue sparing in patients with cervical cancer: An IMRT planning study.
 
During cervical cancer treatment, target volumes change position and shape due to organ motion and tumour regression. An MRI-accelerator will provide information on these changes by online magnetic resonance imaging (MRI) guidance throughout each treatment fraction. The purpose of this intensity-modulated radiation therapy (IMRT) planning study is to assess the benefit of online MRI guidance in healthy tissue sparing... [+ leia mais]
Colaborador: Camila Pessoa de Sales.
Fonte: Radiotherapy and Oncology.
 
 
A phantom study of dose compensation behind hip prosthesis using portal dosimetry and dynamic MLC.
 
A dose compensation method is presented for patients with hip prosthesis based on Dynamic Multi Leaves Collimator (DMLC) planning. Calculations are done from an exit Portal Dose Image (PDI) from 6 MV Photon beam using an Electronic Portal Imaging Device (EPID) from Varian. Four different hip prostheses are used for this work... [+ leia mais]
Colaborador: Camila Pessoa de Sales.
Fonte: Radiotherapy and Oncology.
 
 
Improving Soft-Tissue Contrast in Four-Dimensional Computed Tomography Images of Liver Cancer Patients Using a Deformable Image Registration Method.
 
To investigate a deformable image registration method to improve soft-tissue contrast in four-dimensional (4D) computed tomography (CT) images of the liver... [+ leia mais]
Fonte: Int J Radiat Oncol Biol Phys.
 
 
Positioning Accuracy in Stereotactic Radiotherapy Using a Mask System With Added Vacuum Mouth Piece and Stereoscopic X-Ray Positioning.
 
For cranial patients receiving stereotactic radiotherapy, we use the Exactrac stereoscopic X-ray system to optimize patient positioning. Patients are immobilized with the BrainLAB Mask System (BrainLAB, Feldkirchen, Germany). We have developed an adapter to this system that accommodates a vacuum mouth piece (VMP)... [+ leia mais]
Fonte: Int J Radiat Oncol Biol Phys.
 
 
Potential of dose optimisation in MRI-based PDR brachytherapy of cervix carcinoma.
 
In this study on PDR treatment planning of utero-vaginal carcinoma, we analysed the dosimetry of traditional X-ray based plans as it presents on MR images. The potential gain of MRI-based dose optimisation was assessed... [+ leia mais]
Colaborador: Camila Pessoa de Sales.
Fonte: Radiotherapy and Oncology.
 
 
Boron neutron capture therapy (BNCT) for glioblastoma multiforme: A phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
 
To evaluate the efficacy and safety of boron neutron capture therapy (BNCT) for glioblastoma multiforme (GBM) using a novel protocol for the boronophenylalanine–fructose (BPA-F) infusion... [+ leia mais]
Colaborador: Camila Pessoa de Sales.
Fonte: Radiotherapy and Oncology.
 
 
Improvement in dose homogeneity with electronic tissue compensation over IMRT and conventional RT in whole brain radiotherapy.
 
To perform a dosimetric analysis of whole brain radiotherapy using electronic tissue compensation (ECOMP) with dynamic multileaf collimation (dMLC) and its comparisons with inverse-planned intensity modulated radiation therapy (IMRT) with optimization constraints and conventional whole brain radiotherapy (WBRT)... [+ leia mais]
Colaborador: Camila Pessoa de Sales.
Fonte: Radiotherapy and Oncology.
 
 
A novel concept of treatment of diffuse or multiple pleural tumors by boron neutron capture therapy (BNCT).
 
Two patients, one with malignant pleural mesothelioma and one with a malignant short spindle cell tumor, received boron neutron capture therapy (BNCT). In each case, the tumors regressed or remained stable in size for 3–6 months following BNCT. No acute or late adverse events higher than grade 2 were observed. [+ leia mais]
Colaborador: Camila Pessoa de Sales.
Fonte: Radiotherapy and Oncology.
 
 
Comparison of Dosimetric and Biologic Effective Dose Parameters for Prostate and Urethra Using 131Cs and 125I for Prostate Permanent Implant...
 
To compare the urethral and prostate absolute and biologic effective doses (BEDs) for 131Cs and 125I prostate permanent implant brachytherapy (PPI)... [+ leia mais]
Fonte: Int J Radiat Oncol Biol Phys.
 
 
Feasibility of a Multigroup Deterministic Solution Method for Three-Dimensional Radiotherapy Dose Calculations.
 
To investigate the potential of a novel deterministic solver, Attila, for external photon beam radiotherapy dose calculations... [+ leia mais]
Fonte: Int J Radiat Oncol Biol Phys.
 
 
The extraction of true profiles for TPS commissioning and its impact on IMRT patient-specific QA.
 
The aim of this work is to investigate the clinical impact of detector size effect on patient specific intensity-modulated radiation therapy (IMRT) quality assurance (QA)... [+ leia mais]
Fonte: Medical Physics.
 
 
A fiducial detection algorithm for real-time image guided IMRT based on simultaneous MV and kV imaging.
 
The advantage of highly conformal dose techniques such as 3DCRT and IMRT is limited by intrafraction organ motion. A new approach to gain near real-time 3D positions of internally implanted fiducial markers is to analyze simultaneous onboard kV beam and treatment MV beam images (from fluoroscopic or electronic portal image devices)... [+ leia mais]
Fonte: Medical Physics.
 
 
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