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ABFM NEWS - Medicina Nuclear
 
A novel method to evaluate gamma camera rotational uniformity and sensitivity variation.
 
An alternative to the conventional method of performing the AAPM Report 52 rotational uniformity and sensitivity test has been developed. In contrast to the conventional method in which a Co-57 sheet source is fastened to the collimator, this new point-source method acquires the images intrinsically using a Tc-99m point source placed near the isocenter of gantry rotation. [+ leia mais]
Colaborador: Cássio Vilela Komatsu.
Fonte: Medical Physics.
 
 
Strategies for Clinical Implementation and Quality Management of PET Tracers.
 
This publication presents strategies for the clinical implementation and quality management of positron emission tomography (PET) tracers. PET methodologies, which visualize in vivo biochemical, physiological and pharmacological processes, have revolutionized patient diagnosis and care. [+ leia mais]
Colaborador: Laura Natal Rodrigues.
Fonte: AIEA.
 
 
MIRD Pamphlet No. 21: A Generalized Schema for Radiopharmaceutical Dosimetry—Standardization of Nomenclature.
 
The internal dosimetry schema of the Medical Internal Radiation Dose (MIRD) Committee of the Society of Nuclear Medicine has provided a broad framework for assessment of the absorbed dose to whole organs, tissue subregions, voxelized tissue structures, and individual cellular compartments for use in both diagnostic and therapeutic nuclear medicine... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: The Journal of Nuclear Medicine.
 
 
MIRD Commentary: Proposed Name for a Dosimetry Unit Applicable to Deterministic Biological Effects—The Barendsen (Bd).
 
The fundamental physical quantity for relating all biologic effects to radiation exposure is the absorbed dose, the energy imparted per unit mass of tissue. Absorbed dose is expressed in units of joules per kilogram (J/kg) and is given the special name gray (Gy)... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: The Journal of Nuclear Medicine.
 
 
Radiation Protection in Newer Medical Imaging Techniques: PET/CT.
 
"Safety Reports Series No. 58: The emergence of hybrid systems, such as positron emission tomography (PET) and computed tomography (PET/CT), has stimulated much interest. This Safety Report reviews radiation protection issues arising from the use of PET/CT and offers guidance on dose management and optimization..." [+ leia mais]
Colaborador: Laura Natal Rodrigues.
Fonte: AIEA.
 
 
Technetium-99m Radiopharmaceuticals: Manufacture of Kits.
 
Technical Reports Series No. 466... [+ leia mais]
Fonte: AIEA.
 
 
SPECT-CT and real-time intraoperative imaging: new tools for sentinel node localization and radioguided surgery?
 
It is more than 30 years. Dr. Ramon Cabanas used lymphography to describe the " sentinel node" in patients with penile carcinoma... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: Journal of Nuclear Medicine and Molecular Imaging.
 
 
Radiation Exposure from Liquid Discharges from I-131-Therapy Rooms into the Piping System of a Hospital Building.
 
"Over 80% of the activity from patients undergoing radioiodine therapy for thyroid cancer is eliminated during the first three days. In our I-131 therapy unit, the number of hospitalized patients has increased from less than 200 in 2004 to more than 300 in 2006..." [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: World Journal of Nuclear Medicine,
 
 
Measurement of the internal dose to families of outpatients treated with 131I for hyperthyroidism.
 
"The aim of this study was to measure the internal dose received by family members from ingestion of radioactive contamination after outpatient therapy... " [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: Journal of Nuclear Medicine and Molecular Imaging.
 
 
MIRD Pamphlet No. 20: The Effect of Model Assumptions on Kidney Dosimetry and Response—Implications for Radionuclide Therapy.
 
Renal toxicity associated with small-molecule radionuclide therapy has been shown to be dose-limiting for many clinical studies. Strategies for maximizing dose to the target tissues while sparing normal critical organs based on absorbed dose and biologic response parameters are commonly used in external-beam therapy... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: The Journal of Nuclear Medicine.
 
 
Operational Radiation Safety for PET-CT, SPECT-CT, and Cyclotron Facilites.
 
Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are well- established and indispensable imaging modalities in modern medicine. State-of-the-art computed tomography (CT) scanners have now been integrated into multi-modality PET-CT and SPECT-CT devices... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: Health Physics Society .
 
 
119Sb—A potent Auger emitter for targeted radionuclide therapy.
 
Auger electron emitting radionuclides in cancer therapy offer the opportunity to deliver a high radiation dose to the tumor cells with high radiotoxicity while minimizing toxicity to normal tissue. We have in this study identified the Auger emitter 119Sb as a potent nuclide for targeted radionuclide therapy based on theoretical dosimetry calculations at a subcellular scale... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: Medical Physics.
 
 
The impact of generator ingrowth time on bone scan quality.
 
This investigation evaluated the impact of the increased presence of technetium-99 in molybdenum-99/technetium-99m generator elute following a long generator ingrowth time on bone scan image quality... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: The Internet Journal of Nuclear Medicine.
 
 
Continuing Education: SPECT/CT.
 
In view of the commercial success of integrated PET/CT scanners, there is an increasing interest in comparable SPECT/CT systems. SPECT in combination with CT enables a direct correlation of anatomic information and functional information, resulting in better localization and definition of scintigraphic findings... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: Journal of Nuclear Medicine.
 
 
Correlation Between External Exposure and Activity in Patients Undergoing 131I Thyroid Cancer Therapy.
 
The uptake and clearance of 131I activity for inpatients undergoing cancer therapy were determined from routine external dose survey measurements. A bi-exponential behavior was found, with the two time constants representing the iodine dynamics in the thyroid on one hand and in the rest of the body on the other... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: Health Physics.
 
 
Comparison of methods to determine accurate dose calibrator activity measurements.
 
In nuclear medicine, liquid radiopharmaceuticals for diagnostic or therapeutic purposes are administered to patients by using various types of syringes with different volumes. The activity of each "dose" must be carefully measured and documented prior to administration using an activity calibrator... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: Journal of Experimental & Clinical Cancer Research
 
 
New NRC Guidance on Release of Patients After 131I Treatment.
 
On May 16 the Nuclear Regulatory Commission NRC) announced the issuance of new guidance to medical licensees addressing the post–radioidine therapy release of patients who might come into contact with infants and/or young children... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: The Journal of Nuclear Medicine.
 
 
Adsorption of 99mTc-Radiopharmaceuticals onto Injection Vials and Syringes.
 
Many groups have reported the adsorption or retention of 99mTc-radiopharmaceuticals on injection vials and disposable plastic syringes. Such an enormously high loss of radioactivity would result in poor images, radiation exposure, waste, and economic burdens... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: Journal of Nuclear Medicine Technology.
 
 
Routine Quality Control of Clinical Nuclear Medicine Instrumentation: A Brief Review.
 
This article reviews routine quality-control (QC) procedures for current nuclear medicine instrumentation, including the survey meter, dose calibrator, well counter, intraoperative probe, organ ("thyroid") uptake probe, -camera, SPECT and SPECT/CT scanner, and PET and PET/CT scanner... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: Journal of Nuclear Medicine.
 
 
Brain Single-Photon Emission Computed Tomography Physics Principles.
 
The basic principles of scintigraphy are reviewed and extended to 3D imaging. Single-photon emission computed tomography (SPECT) is a sensitive and specific 3D technique to monitor in vivo functional processes in both clinical and preclinical studies... [+ leia mais]
Colaborador: Rodrigo Biancardi.
Fonte: American Journal of Neuroradiology.
 
 
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