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ABFM NEWS - Radioterapia
 
Dose Gradient Near Target–Normal Structure Interface for Nonisocentric CyberKnife and Isocentric Intensity-Modulated Body Radiotherapy for Prostate Ca
 
"Purpose The treatment planning quality between nonisocentric CyberKnife (CK) and isocentric intensity modulation treatment was studied for hypofractionated prostate body radiotherapy. In particular, the dose gradient across the target and the critical structures such as the rectum and bladder was characterized. " [+ leia mais]
Fonte: Int J of Radiation Oncology, Biology & Physics
 
 
Correlation Between Acute and Late Toxicity in 973 Prostate Cancer Patients Treated With Three-Dimensional Conformal External Beam Radiotherapy
 
"Purpose To analyze the correlation between acute and late injury in 973 prostate cancer patients treated with radiotherapy and to evaluate the effect of patient-, tumor-, and treatment-related variables on toxicity." [+ leia mais]
Fonte: Int J of Radiation Oncology, Biology & Physics
 
 
CT-guided iodine-125 seed permanent implantation for recurrent head and neck cancers
 
"Background To investigate the feasibility, and safety of 125I seed permanent implantation for recurrent head and neck carcinoma under CT-guidance." [+ leia mais]
Fonte: Radiation Oncology
 
 
Validation of bidimensional measurement in nasopharyngeal carcinoma
 
"Background Our previous study showed a close relationship between computed tomography (CT)-derived bidimensional measurement of primary tumor and retropharyngeal nodes (BDMprn) and gross tumor volume of primary tumor and retropharyngeal nodes ( GTVprn) in nasopharyngeal carcinoma (NPC) and better prognosis for NPC patients with smaller BDMprn. In this study, we report the results on of a study to validate the use of BDM in a separate cohort of NPC patients." [+ leia mais]
Fonte: Radiation Oncology
 
 
Small photon beam measurements using radiochromic film and Monte Carlo simulations in a water phantom
 
"Abstract This work reports the use of both GafChromic EBT film immersed in a water phantom and Monte Carlo (MC) simulations for small photon beam stereotactic radiosurgery dosimetry. Circularly collimated photon beams with diameters in the 4–20 mm range of a dedicated 6 MV linear accelerator (Novalis®, BrainLAB, Germany) were used to perform off-axis ratios, tissue maximum ratios and total scatter factors measurements, and MC simulations. GafChromic EBT film data show an excellent agreement with MC results (<2.7%) for all measured quantities. " [+ leia mais]
Fonte: Radiotherapy and Oncology
 
 
Simulating demand for innovative radiotherapies: An illustrative model based on carbon ion and proton radiotherapy
 
"Background and purpose Innovative therapies are not only characterized by major uncertainties regarding clinical benefit and cost but also the expected recruitment of patients. An original model was developed to simulate patient recruitment to a costly particle therapy by varying layout of the facility and patient referral (one vs. several countries) and by weighting the treated indication by the expected benefit of particle therapy." [+ leia mais]
Fonte: Radiotherapy and Oncology
 
 
Dosimetric effect of setup motion and target volume margin reduction in pediatric ependymoma
 
"Purpose Quantify the dosimetric effect of inter- and intrafractional motion on intensity-modulated radiation therapy (IMRT) and three-dimensional (3D) planning via changes in the generalized equivalent uniform dose (gEUD), predicted tumor control probability (TCP) and normal tissue complication probability (NTCP) for pediatric ependymoma." [+ leia mais]
Fonte: Radiotherapy and Oncology
 
 
A method to improve target dose homogeneity of craniospinal irradiation using dynamic split field IMRT
 
"Purpose Craniospinal irradiation (CSI) is technically very challenging and field edge matching is needed because of the mechanical limitations of standard linear accelerators. We assessed the feasibility of intensity-modulated radiotherapy (IMRT) in CSI to overcome the standard feathering and dose inhomogeneities associated with the standard feathering technique in the junction areas." [+ leia mais]
Fonte: Radiotherapy and Oncology
 
 
Boosting the tumor bed from deep-seated tumors in early-stage breast cancer: A planning study between electron, photon, and proton beams
 
"Purpose To assess the potential dosimetric advantages and drawbacks of photon beams (modulated or not), electron beams (EB), and protons as a boost for the tumor bed in deep-seated early-stage breast cancer." [+ leia mais]
Fonte: Radiotherapy and Oncology
 
 
Dosimetric evolution of the breast electron boost target using 3D ultrasound imaging
 
"Purpose To investigate the effect of treatment planning, patient setup, and interfraction motion errors on the delivered dose for external beam electron boosts for postoperative early stage breast cancer patients." [+ leia mais]
Fonte: Radiotherapy and Oncology
 
 
Evaluation of the ‘dose of the day’ for IMRT prostate cancer patients derived from portal dose measurements and cone-beam CT
 
"Abstract Purpose High geometrical and dosimetrical accuracies are required for radiotherapy treatments where IMRT is applied in combination with narrow treatment margins in order to minimize dose delivery to normal tissues. As an overall check, we implemented a method for reconstruction of the actually delivered 3D dose distribution to the patient during a treatment fraction, i.e., the ‘dose of the day’. In this article results on the clinical evaluation of this concept for a group of IMRT prostate cancer patients are presented. " [+ leia mais]
Fonte: Radiotherapy and Oncology
 
 
An analysis of intraoperative versus post-operative dosimetry with CT, CT–MRI fusion and XMR for the evaluation of permanent prostate brachytherapy im
 
"Abstract Background and purpose To assess the agreement between intraoperative and post-operative dosimetry and to identify factors that influence dose calculations of prostate brachytherapy implants. " [+ leia mais]
Fonte: Radiotherapy and Oncology
 
 
MRI-based low dose-rate brachytherapy experience in locally advanced cervical cancer patients initially treated by concomitant chemoradiotherapy
 
"Abstract Purpose To retrospectively assess the physics contributions and the clinical outcome with preliminary 3D MRI-guided low dose-rate (LDR) intracavitary brachytherapy (BT) experience in locally advanced cervical cancer patients " [+ leia mais]
Fonte: Radiotherapy and Oncology
 
 
Validation of a treatment plan-based calibration method for 2D detectors used for treatment delivery quality assurance
 
Purpose: Dosimetry using film, CR, electronic portal imaging, or other 2D detectors requires calibration of the raw image data to obtain dose. Typically, a series of known doses are given to the detector, the raw signal for each dose is obtained, and a calibration curve is created. [+ leia mais]
Colaborador: Laura Natal Rodrigues
Fonte: Medical Physics
 
 
Prone versus supine positioning for whole and partial-breast radiotherapy: A comparison of non-target tissue dosimetry
 
"Purpose To compare non-target tissue (including left-anterior-descending coronary-artery (LAD)) dosimetry of prone versus supine whole (WBI) and partial-breast irradiation (PBI)." [+ leia mais]
Fonte: Radiotherapy and Oncology
 
 
Evaluation of the ‘dose of the day’ for IMRT prostate cancer patients derived from portal dose measurements and cone-beam CT
 
"Purpose High geometrical and dosimetrical accuracies are required for radiotherapy treatments where IMRT is applied in combination with narrow treatment margins in order to minimize dose delivery to normal tissues. As an overall check, we implemented a method for reconstruction of the actually delivered 3D dose distribution to the patient during a treatment fraction, i.e., the ‘dose of the day’. In this article results on the clinical evaluation of this concept for a group of IMRT prostate cancer patients are presented." [+ leia mais]
Fonte: Radiotherapy and Oncology
 
 
MRI-based low dose-rate brachytherapy experience in locally advanced cervical cancer patients initially treated by concomitant chemoradiotherapy
 
"Purpose To retrospectively assess the physics contributions and the clinical outcome with preliminary 3D MRI-guided low dose-rate (LDR) intracavitary brachytherapy (BT) experience in locally advanced cervical cancer patients." [+ leia mais]
Fonte: Radiotherapy and Oncology
 
 
Prospective multi-center trial utilizing electronic brachytherapy for the treatment of endometrial cancer
 
"Background A modified form of high dose rate (HDR) brachytherapy has been developed called Axxent Electronic Brachytherapy (EBT). EBT uses a kilovolt X-ray source and does not require treatment in a shielded vault or a HDR afterloader unit. A multi-center clinical study was carried out to evaluate the success of treatment delivery, safety and toxicity of EBT in patients with endometrial cancer." [+ leia mais]
Fonte: Radiation Oncology
 
 
Intensity-Modulated Radiotherapy in Patients with Cervical Cancer. An intra-individual Comparison of Prone and Supine Positioning
 
"Background Chemoradiation for cervical cancer patients is associated with considerable gastrointestinal toxicity. Intensity-modulated radiotherapy (IMRT) has demonstrated superiority in terms of target coverage and normal tissue sparing in comparison to conventional 3D planning in gynaecological malignancies. Whether IMRT in prone (PP) or supine position (SP) might be beneficial for cervical cancer patients remains partially unanswered." [+ leia mais]
Fonte: Radiation Oncology
 
 
Enhanced epidermal dose caused by localized electron contamination from lead cutouts used in kilovoltage radiotherapy
 
"Purpose: To investigate and quantify electron contamination from the lead cutouts used in kilovoltage x-ray radiotherapy." [+ leia mais]
Fonte: Medical Physics
 
 
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